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Creators/Authors contains: "Tan, Philip"

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  1. Ultrasonic imaging is one of the most powerful and commonplace medical tools for noninvasive visualization of soft tissues inside the body. However, ultrasonography requires highly trained sonographers to position and orient the transducer on the surface of the patient’s body, and image quality is highly dependent on the steadiness of the operator’s hand. Because of this, ultrasonic imaging has been largely limited to short and static sessions not only for logistical reasons but also because of the very real threat of musculoskeletal injuries for sonographers from repetitive motions associated with transducer manipulation ( 1 ). Coincidentally, there has also been a sonographer shortage worldwide over the past decade, and the demanding and specialized training required for certifying sonographers does not help alleviate this problem ( 2 ). On page 517 of this issue, Wang et al. ( 3 ) introduce a bioadhesive ultrasound (BAUS) patch with the potential to overcome many of these outstanding challenges. 
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  2. Abstract Cardiovascular diseases are the leading cause of death globally. Noninvasive, accurate, and continuous cardiovascular monitoring can enable the preemptive detection of heart diseases and timely intervention to prevent serious cardiac complications. However, unobtrusive, ambulatory, and comprehensive cardiac monitoring is still a challenge as conventional electronics are rigid, heavy, or consume too much power for long‐term measurement. This work presents a thin (200 µm), stretchable (20%), lightweight (2.5 g), wireless, and low‐power (<3 mW) cardiac monitoring device that conforms to the human chest like a temporary tattoo sticker, correspondingly known as an e‐tattoo. This chest e‐tattoo features dual‐mode electro‐mechanical sensing—bio‐electric cardiac signals via electrocardiography and mechanical cardiac rhythm via seismocardiography. A unique peripheral synchronization strategy between the two sensors enables the measurement of systolic time intervals like the pre‐ejection period and the left ventricular ejection time with high accuracy (error = −0.44 ± 8.74 ms) while consuming very low power. The e‐tattoo is validated against clinically approved gold‐standard instruments on five human subjects. The good wearability and low power consumption of this e‐tattoo permit 24‐h continuous ambulatory monitoring. 
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